ALDOB anticorps
Aperçu rapide pour ALDOB anticorps (ABIN2715928)
Antigène
Voir toutes ALDOB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Attributs du produit
- Homo sapiens aldolase B, fructose-bisphosphate (ALDOB)
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Purification
- Purified from mouse ascites fluids by affinity chromatography
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Immunogène
- Full length human recombinant protein of human ALDOB(NP_000026) produced in HEK293 cell.
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Isotype
- IgG2b
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Indications d'application
- WB 1:2000, IHC 1:150, FLOW 1:100,
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Commentaires
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The concentration of the product may vary between diferrent lots.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5-1.0 mg/mL
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Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))
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Autre désignation
- ALDOB
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Sujet
- Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5 % of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.
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Poids moléculaire
- 39.3 kDa
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ID gène
- 229
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NCBI Accession
- NM_000035
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HGNC
- 229
Antigène
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